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ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy.
Xiao, Xiangling; Shi, Jie; He, Chuan; Bu, Xia; Sun, Yishuang; Gao, Minling; Xiang, Bolin; Xiong, Wenjun; Dai, Panpan; Mao, Qi; Xing, Xixin; Yao, Yingmeng; Yu, Haisheng; Xu, Gaoshan; Li, Siqi; Ren, Yan; Chen, Baoxiang; Jiang, Congqing; Meng, Geng; Lee, Yu-Ru; Wei, Wenyi; Freeman, Gordon J; Xie, Conghua; Zhang, Jinfang.
Afiliação
  • Xiao X; Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University; Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.
  • Shi J; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, 430071, China.
  • He C; Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University; Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.
  • Bu X; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, 430071, China.
  • Sun Y; Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University; Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.
  • Gao M; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, 430071, China.
  • Xiang B; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02115, USA.
  • Xiong W; Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University; Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.
  • Dai P; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, 430071, China.
  • Mao Q; Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University; Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.
  • Xing X; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, 430071, China.
  • Yao Y; Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University; Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.
  • Yu H; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, 430071, China.
  • Xu G; Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University; Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.
  • Li S; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, 430071, China.
  • Ren Y; Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University; Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.
  • Chen B; Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University; Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.
  • Jiang C; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, 430071, China.
  • Meng G; Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University; Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.
  • Lee YR; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, 430071, China.
  • Wei W; Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University; Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.
  • Freeman GJ; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, 430071, China.
  • Xie C; Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University; Medical Research Institute, Frontier Science Center of Immunology and Metabolism, Wuhan University, Wuhan, 430071, China.
  • Zhang J; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, 430071, China.
Nat Commun ; 14(1): 2859, 2023 05 19.
Article em En | MEDLINE | ID: mdl-37208329

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MAP Quinases Reguladas por Sinal Extracelular / Receptor de Morte Celular Programada 1 Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MAP Quinases Reguladas por Sinal Extracelular / Receptor de Morte Celular Programada 1 Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China