Pilot-scale production of inactivated monoglycosylated split H<sub>1</sub>N<sub>1</sub> influenza virus vaccine provides cross-strain protection against influenza viruses.

Wu, Chia-Ying; Kao, Shao-En; Tseng, Yung-Chieh; Lin, Yu-Po; Hou, Jen-Tzu; Wu, Li-Yang; Chiu, Sharon; Ma, Che Alex; Hsiao, Pei-Wen; Hsiao, Jane; Chen, Juine-Ruey

Pilot-scale production of inactivated monoglycosylated split H₁N₁ influenza virus vaccine provides cross-strain protection against influenza viruses.

Wu, Chia-Ying; Kao, Shao-En; Tseng, Yung-Chieh; Lin, Yu-Po; Hou, Jen-Tzu; Wu, Li-Yang; Chiu, Sharon; Ma, Che Alex; Hsiao, Pei-Wen; Hsiao, Jane; Chen, Juine-Ruey.

Afiliação

Wu CY; RuenHuei Biopharmaceuticals Inc. Taipei, Taiwan.
Kao SE; RuenHuei Biopharmaceuticals Inc. Taipei, Taiwan.
Tseng YC; RuenHuei Biopharmaceuticals Inc. Taipei, Taiwan.
Lin YP; RuenHuei Biopharmaceuticals Inc. Taipei, Taiwan.
Hou JT; RuenHuei Biopharmaceuticals Inc. Taipei, Taiwan.
Wu LY; RuenHuei Biopharmaceuticals Inc. Taipei, Taiwan.
Chiu S; RuenHuei Biopharmaceuticals Inc. Taipei, Taiwan.
Ma CA; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
Hsiao PW; Agricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan.
Hsiao J; RuenHuei Biopharmaceuticals Inc. Taipei, Taiwan; OPKO Health Inc. Miami, Florida, USA.
Chen JR; RuenHuei Biopharmaceuticals Inc. Taipei, Taiwan. Electronic address: jrchen@rhbiopharma.com.

Antiviral Res ; 216: 105640, 2023 08.

Article em En | MEDLINE | ID: mdl-37263355

Assuntos

Vírus da Influenza A Subtipo H1N1; Vacinas contra Influenza; Influenza Humana; Infecções por Orthomyxoviridae; Animais; Camundongos; Humanos; Anticorpos Antivirais; Vacinas de Produtos Inativados; Glicoproteínas de Hemaglutininação de Vírus da Influenza

Palavras-chave

ADCC activity; Balanced B and T cell response; Cross-strain protection; HA head domain and HAstem antibodies; Monoglycosylated influenza vaccine; Monoglycosylated neuraminidase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas contra Influenza / Infecções por Orthomyxoviridae / Influenza Humana / Vírus da Influenza A Subtipo H1N1 Limite: Animals / Humans Idioma: En Revista: Antiviral Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Taiwan

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