An electroaffinity labelling platform for chemoproteomic-based target identification.

Kawamata, Yu; Ryu, Keun Ah; Hermann, Gary N; Sandahl, Alexander; Vantourout, Julien C; Olow, Aleksandra K; Adams, La-Tonya A; Rivera-Chao, Eva; Roberts, Lee R; Gnaim, Samer; Nassir, Molhm; Oslund, Rob C; Fadeyi, Olugbeminiyi O; Baran, Phil S

Kawamata, Yu; Ryu, Keun Ah; Hermann, Gary N; Sandahl, Alexander; Vantourout, Julien C; Olow, Aleksandra K; Adams, La-Tonya A; Rivera-Chao, Eva; Roberts, Lee R; Gnaim, Samer; Nassir, Molhm; Oslund, Rob C; Fadeyi, Olugbeminiyi O; Baran, Phil S.

Afiliação

Kawamata Y; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Ryu KA; Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA.
Hermann GN; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Sandahl A; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Vantourout JC; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Olow AK; Genetics and Pharmacogenomics, Merck & Co., Inc., San Francisco, CA, USA.
Adams LA; Discovery Immunology, Merck & Co., Inc., Cambridge, MA, USA.
Rivera-Chao E; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Roberts LR; Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA.
Gnaim S; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Nassir M; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Oslund RC; Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA. rob@induprotx.com.
Fadeyi OO; InduPro Therapeutics, Cambridge, MA, USA. rob@induprotx.com.
Baran PS; Exploratory Science Center, Merck & Co., Inc., Cambridge, MA, USA. niyi@induprotx.com.

Nat Chem ; 15(9): 1267-1275, 2023 09.

Article em En | MEDLINE | ID: mdl-37322100

Assuntos

Descoberta de Drogas; Proteínas; Proteínas/metabolismo; Marcadores de Fotoafinidade/química; Ligantes; Farmacóforo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas / Descoberta de Drogas Tipo de estudo: Diagnostic_studies Idioma: En Revista: Nat Chem Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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