IL-17A induces valvular endothelial inflammation and aggravates calcific aortic valve disease.

Yang, Zhao; Zhang, Jichao; Zhu, Yuexin; Zhang, Congcong; Li, Guang; Liu, Shuo; Du, Jie; Han, Yingchun; You, Bin

Yang, Zhao; Zhang, Jichao; Zhu, Yuexin; Zhang, Congcong; Li, Guang; Liu, Shuo; Du, Jie; Han, Yingchun; You, Bin.

Afiliação

Yang Z; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing, China.
Zhang J; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing, China.
Zhu Y; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing, China.
Zhang C; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing, China.
Li G; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing, China.
Liu S; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing, China.
Du J; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing, China.
Han Y; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing, China. Electronic address: hanyingchun.wfl@163.com.
You B; Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing, China. Electronic address: dr_youbin@vip.sina.com.

Biochem Biophys Res Commun ; 672: 145-153, 2023 09 10.

Article em En | MEDLINE | ID: mdl-37354607

Assuntos

Estenose da Valva Aórtica; Valva Aórtica; Humanos; Camundongos; Animais; Valva Aórtica/metabolismo; Subunidade alfa 1 de Fator de Ligação ao Core/metabolismo; Células Endoteliais/metabolismo; Interleucina-17/metabolismo; Estenose da Valva Aórtica/genética; Citocinas/metabolismo; Inflamação/patologia; Fibrose; Apolipoproteínas E/metabolismo; Células Cultivadas

Palavras-chave

Calcific aortic valve disease; Fibrosis; IL-17A; Inflammation; Valve endothelial cells

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Valva Aórtica / Estenose da Valva Aórtica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google