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The NLRP3 inflammasome in viral infection (Review).
Zheng, Qiaoli; Hua, Chunting; Liang, Qichang; Cheng, Hao.
Afiliação
  • Zheng Q; Department of Dermatology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.
  • Hua C; Department of Dermatology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.
  • Liang Q; Department of Dermatology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.
  • Cheng H; Department of Dermatology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.
Mol Med Rep ; 28(3)2023 Sep.
Article em En | MEDLINE | ID: mdl-37417336
The interplay between pathogen and host determines the immune response during viral infection. The Nod­like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL­1ß, which play an important role in the innate immune responses. In the present review, the mechanisms of the NLR family pyrin domain containing 3 inflammasome activation and its dysregulation in viral infection were addressed.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Viroses / Inflamassomos Limite: Humans Idioma: En Revista: Mol Med Rep Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Viroses / Inflamassomos Limite: Humans Idioma: En Revista: Mol Med Rep Ano de publicação: 2023 Tipo de documento: Article