The interplay of DNA repair context with target sequence predictably biasses Cas9-generated mutations.

Pallaseni, Ananth; Peets, Elin Madli; Girling, Gareth; Crepaldi, Luca; Kuzmin, Ivan; Raudvere, Uku; Peterson, Hedi; Serçin, Özdemirhan; Mardin, Balca R; Kosicki, Michael; Parts, Leopold

Pallaseni, Ananth; Peets, Elin Madli; Girling, Gareth; Crepaldi, Luca; Kuzmin, Ivan; Raudvere, Uku; Peterson, Hedi; Serçin, Özdemirhan; Mardin, Balca R; Kosicki, Michael; Parts, Leopold.

Afiliação

Pallaseni A; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Peets EM; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Girling G; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Crepaldi L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Kuzmin I; Department of Computer Science, University of Tartu, Tartu, Estonia.
Raudvere U; Department of Computer Science, University of Tartu, Tartu, Estonia.
Peterson H; Department of Computer Science, University of Tartu, Tartu, Estonia.
Serçin Ö; BioMed X Institute (GmbH), Im Neuenheimer Feld 515, Heidelberg, Germany.
Mardin BR; BioMed X Institute (GmbH), Im Neuenheimer Feld 515, Heidelberg, Germany.
Kosicki M; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.
Parts L; Lawrence Berkeley National Laboratory, Berkeley, California, USA.

bioRxiv ; 2023 Jun 28.

Article em En | MEDLINE | ID: mdl-37425722

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google