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Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential.
Martinez, David R; Moreira, Fernando R; Zweigart, Mark R; Gully, Kendra L; De la Cruz, Gabriela; Brown, Ariane J; Adams, Lily E; Catanzaro, Nicholas; Yount, Boyd; Baric, Thomas J; Mallory, Michael L; Conrad, Helen; May, Samantha R; Dong, Stephanie; Scobey, D Trevor; Montgomery, Stephanie A; Perry, Jason; Babusis, Darius; Barrett, Kimberly T; Nguyen, Anh-Hoa; Nguyen, Anh-Quan; Kalla, Rao; Bannister, Roy; Bilello, John P; Feng, Joy Y; Cihlar, Tomas; Baric, Ralph S; Mackman, Richard L; Schäfer, Alexandra; Sheahan, Timothy P.
Afiliação
  • Martinez DR; Department of Immunobiology, Yale School of Medicine, New Haven, CT, 06510, USA.
  • Moreira FR; Yale Center for Infection and Immunity, Yale School of Medicine, New Haven, CT, 06510, USA.
  • Zweigart MR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Gully KL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • De la Cruz G; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Brown AJ; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
  • Adams LE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Catanzaro N; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Yount B; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Baric TJ; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Mallory ML; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Conrad H; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • May SR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Dong S; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Scobey DT; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Montgomery SA; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Perry J; Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
  • Babusis D; Gilead Sciences, Inc, Foster City, CA, USA.
  • Barrett KT; Gilead Sciences, Inc, Foster City, CA, USA.
  • Nguyen AH; Gilead Sciences, Inc, Foster City, CA, USA.
  • Nguyen AQ; Gilead Sciences, Inc, Foster City, CA, USA.
  • Kalla R; Gilead Sciences, Inc, Foster City, CA, USA.
  • Bannister R; Gilead Sciences, Inc, Foster City, CA, USA.
  • Bilello JP; Gilead Sciences, Inc, Foster City, CA, USA.
  • Feng JY; Gilead Sciences, Inc, Foster City, CA, USA.
  • Cihlar T; Gilead Sciences, Inc, Foster City, CA, USA.
  • Baric RS; Gilead Sciences, Inc, Foster City, CA, USA.
  • Mackman RL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Schäfer A; Rapidly Emerging Antiviral Drug Development Initiative, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Sheahan TP; Gilead Sciences, Inc, Foster City, CA, USA.
bioRxiv ; 2023 Jun 28.
Article em En | MEDLINE | ID: mdl-37425890
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos