Lymphomas affecting the submandibular glands.
Med Oral Patol Oral Cir Bucal
; 29(1): e78-e86, 2024 Jan 01.
Article
em En
| MEDLINE
| ID: mdl-37471301
ABSTRACT
BACKGROUND:
Lymphomas affecting the submandibular glands are very uncommon and few reports are currently available in the literature. Therefore, the aim of the current study is to describe the clinical and microscopic features of an original series of lymphomas affecting the submandibular glands. MATERIAL ANDMETHODS:
The pathology files of two institutions were searched for lymphoma cases affecting the submandibular glands. The original hematoxylin and eosin, and immunohistochemical slides were revised by a pathologist for diagnosis confirmation following the revised 4th edition of the World Health Organization classification of tumours of haematopoietic and lymphoid tissues. Clinical data regarding age, sex, clinical manifestation, treatment, follow-up and status at last appointment were retrieved from the patients' medical charts.RESULTS:
During the period investigated, 16 cases were included in the study. Females predominated (106) with a mean age of 57.8 years-old. Tumors usually presented as asymptomatic swellings. MALT lymphoma represented the most common subtype, followed by diffuse large B cell lymphoma and follicular lymphoma. Three patients died, one of them affected by plasmablastic lymphoma, one by DLBCL and one by MALT lymphoma.CONCLUSIONS:
Low-grade B cell lymphomas predominate in the submandibular glands, but DLBCL and other subtypes may also be rarely diagnosed in this salivary gland.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linfoma Difuso de Grandes Células B
/
Linfoma de Zona Marginal Tipo Células B
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Med Oral Patol Oral Cir Bucal
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Brasil