ER chaperone GRP78/BiP translocates to the nucleus under stress and acts as a transcriptional regulator.

Liu, Ze; Liu, Guanlin; Ha, Dat P; Wang, Justin; Xiong, Min; Lee, Amy S

Liu, Ze; Liu, Guanlin; Ha, Dat P; Wang, Justin; Xiong, Min; Lee, Amy S.

Afiliação

Liu Z; Department of Biochemistry and Molecular Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033.
Liu G; Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033.
Ha DP; Department of Biochemistry and Molecular Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033.
Wang J; Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033.
Xiong M; Department of Biochemistry and Molecular Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033.
Lee AS; Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033.

Proc Natl Acad Sci U S A ; 120(31): e2303448120, 2023 08.

Article em En | MEDLINE | ID: mdl-37487081

Assuntos

Núcleo Celular; Chaperona BiP do Retículo Endoplasmático; Humanos; Carcinogênese; Movimento Celular; Transformação Celular Neoplásica

Palavras-chave

ER stress; GRP78; lung cancer; nuclear translocation; transcriptional regulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Núcleo Celular / Chaperona BiP do Retículo Endoplasmático Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2023 Tipo de documento: Article

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