Carbon 14 and stable isotope synthesis of two potent and selective phosphodiesterase type 4 inhibitors.

Latli, Bachir; Hrapchak, Matt J; Tampone, Thomas G; Frutos, Rogelio P; Lee, Heewon

Latli, Bachir; Hrapchak, Matt J; Tampone, Thomas G; Frutos, Rogelio P; Lee, Heewon.

Afiliação

Latli B; The Radiosynthesis Laboratory, Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, USA.
Hrapchak MJ; The Radiosynthesis Laboratory, Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, USA.
Tampone TG; The Radiosynthesis Laboratory, Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, USA.
Frutos RP; The Radiosynthesis Laboratory, Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, USA.
Lee H; The Radiosynthesis Laboratory, Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, USA.

J Labelled Comp Radiopharm ; 66(11): 353-361, 2023 09.

Article em En | MEDLINE | ID: mdl-37487707

Assuntos

Inibidores da Fosfodiesterase 4; Radioisótopos de Carbono; Piperazina; Ureia; Estereoisomerismo

Palavras-chave

PDE4 inhibitors; carbon 13; carbon 14; deuterium; radiosynthesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Fosfodiesterase 4 Idioma: En Revista: J Labelled Comp Radiopharm Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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