Spatial Omics Sequencing Based on Microfluidic Array Chips.
Biosensors (Basel)
; 13(7)2023 Jul 06.
Article
em En
| MEDLINE
| ID: mdl-37504111
ABSTRACT
Spatial profiling technologies fill the gap left by the loss of spatial information in traditional single-cell sequencing, showing great application prospects. After just a few years of quick development, spatial profiling technologies have made great progress in resolution and simplicity. This review introduces the development of spatial omics sequencing based on microfluidic array chips and describes barcoding strategies using various microfluidic designs with simplicity and efficiency. At the same time, the pros and cons of each strategy are compared. Moreover, commercialized solutions for spatial profiling are also introduced. In the end, the future perspective of spatial omics sequencing and research directions are discussed.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Microfluídica
Idioma:
En
Revista:
Biosensors (Basel)
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
China