<i>Tiliacora triandra</i> Leaf Powder Ethanolic Extract in Combination with Cisplatin or Gemcitabine Synergistically Inhibits the Growth of Cholangiocarcinoma Cells In Vitro and in Nude Mouse Xenograft Models.

Samankul, Arunta; Senawong, Gulsiri; Utaiwat, Suppawit; Prompipak, Jeerati; Woranam, Khanutsanan; Phaosiri, Chanokbhorn; Sripa, Banchob; Senawong, Thanaset

Tiliacora triandra Leaf Powder Ethanolic Extract in Combination with Cisplatin or Gemcitabine Synergistically Inhibits the Growth of Cholangiocarcinoma Cells In Vitro and in Nude Mouse Xenograft Models.

Samankul, Arunta; Senawong, Gulsiri; Utaiwat, Suppawit; Prompipak, Jeerati; Woranam, Khanutsanan; Phaosiri, Chanokbhorn; Sripa, Banchob; Senawong, Thanaset.

Afiliação

Samankul A; Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Senawong G; Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Utaiwat S; Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Prompipak J; Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Woranam K; Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Phaosiri C; Department of Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Sripa B; WHO Collaborating Centre for Research and Control of Opisthorchiasis (Southeast Asian Liver Fluke Disease), Tropical Disease Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Senawong T; Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.

Medicina (Kaunas) ; 59(7)2023 Jul 07.

Article em En | MEDLINE | ID: mdl-37512080

Assuntos

Neoplasias dos Ductos Biliares; Colangiocarcinoma; Humanos; Animais; Camundongos; Gencitabina; Cisplatino/farmacologia; Cisplatino/uso terapêutico; Camundongos Nus; Xenoenxertos; Pós/farmacologia; Pós/uso terapêutico; Desoxicitidina/farmacologia; Desoxicitidina/uso terapêutico; Apoptose; Colangiocarcinoma/tratamento farmacológico; Proliferação de Células; Neoplasias dos Ductos Biliares/tratamento farmacológico; Ductos Biliares Intra-Hepáticos; Proteínas Proto-Oncogênicas c-bcl-2; Linhagem Celular Tumoral; Protocolos de Quimioterapia Combinada Antineoplásica/farmacologia; Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico

Palavras-chave

Tiliacora triandra; anticancer activity; cholangiocarcinoma; cisplatin; drug combination; gemcitabine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias dos Ductos Biliares / Colangiocarcinoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Medicina (Kaunas) Assunto da revista: MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Tailândia

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