Projection of Target Drug Particle Size in Oral Formulations Using the Refined Developability Classification System (rDCS).

Beran, Kristian; Hermans, Eline; Holm, René; Sepassi, Kia; Dressman, Jennifer

Beran, Kristian; Hermans, Eline; Holm, René; Sepassi, Kia; Dressman, Jennifer.

Afiliação

Beran K; Fraunhofer Institute of Translational Medicine and Pharmacology, 60596 Frankfurt am Main, Germany.
Hermans E; Janssen Research & Development, Pharmaceutical & Material Sciences, 2340 Beerse, Belgium.
Holm R; Janssen Research & Development, Pharmaceutical & Material Sciences, 2340 Beerse, Belgium.
Sepassi K; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, 5230 Odense, Denmark.
Dressman J; Janssen Research & Development, Discovery Pharmaceutics, La Jolla, CA 92121, USA.

Pharmaceutics ; 15(7)2023 Jul 08.

Article em En | MEDLINE | ID: mdl-37514095

Palavras-chave

dissolution limitations; oral drug absorption; particle size; permeability; refined developability classification system (rDCS); transit

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha

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