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Numerical investigation of the dynamics of a rigid spherical particle in a vortical cross-slot flow at moderate inertia.
Kechagidis, Konstantinos; Owen, Benjamin; Guillou, Lionel; Tse, Henry; Di Carlo, Dino; Krüger, Timm.
Afiliação
  • Kechagidis K; School of Engineering, Institute for Multiscale Thermofluids, University of Edinburgh, W Mains Rd, Edinburgh, EH9 3JW Scotland UK.
  • Owen B; School of Engineering, Institute for Multiscale Thermofluids, University of Edinburgh, W Mains Rd, Edinburgh, EH9 3JW Scotland UK.
  • Guillou L; Cytovale, Inc., Executive Park Blvd., San Fransisco, CA 90095 CA USA.
  • Tse H; Cytovale, Inc., Executive Park Blvd., San Fransisco, CA 90095 CA USA.
  • Di Carlo D; Department of Bioengineering, University of California, Westwood Plaza, Los Angeles, 610101 CA USA.
  • Krüger T; School of Engineering, Institute for Multiscale Thermofluids, University of Edinburgh, W Mains Rd, Edinburgh, EH9 3JW Scotland UK.
Microsyst Nanoeng ; 9: 100, 2023.
Article em En | MEDLINE | ID: mdl-37519826
ABSTRACT
The study of flow and particle dynamics in microfluidic cross-slot channels is of high relevance for lab-on-a-chip applications. In this work, we investigate the dynamics of a rigid spherical particle in a cross-slot junction for a channel height-to-width ratio of 0.6 and at a Reynolds number of 120 for which a steady vortex exists in the junction area. Using an in-house immersed-boundary-lattice-Boltzmann code, we analyse the effect of the entry position of the particle in the junction and the particle size on the dynamics and trajectory shape of the particle. We find that the dynamics of the particle depend strongly on its lateral entry position in the junction and weakly on its vertical entry position; particles that enter close to the centre show trajectory oscillations. Larger particles have longer residence times in the junction and tend to oscillate less due to their confinement. Our work contributes to the understanding of particle dynamics in intersecting flows and enables the design of optimised geometries for cytometry and particle manipulation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Microsyst Nanoeng Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Microsyst Nanoeng Ano de publicação: 2023 Tipo de documento: Article