Postmortem Ultrastructural Analysis of the Retina from COVID-19 Deceased Patients.
Ocul Immunol Inflamm
; : 1-9, 2023 Aug 08.
Article
em En
| MEDLINE
| ID: mdl-37552861
ABSTRACT
PURPOSE:
COVID-19 (coronavirus disease 2019) is an infectious disease caused by SARS-CoV-2, first reported in 2019 in Wuhan, China. Among the common complications is a pro-inflammatory and hypercoagulative response that compromises the vasculature among various organs.METHODS:
In this report, we present the postmortem retinal findings of five patients observed by means of optical microscopy and transmission and scanning electron microscopy techniques.RESULTS:
Clinical manifestations such as retinal hemorrhages and exacerbated inflammatory infiltrate, altered ultra structure with swollen mitochondria and pyknotic cells in both layers of the retina were observed in all analyzed eyes.CONCLUSION:
Our data point to the fragility of this tissue in cases of severe COVID-19.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Ocul Immunol Inflamm
Assunto da revista:
ALERGIA E IMUNOLOGIA
/
OFTALMOLOGIA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Brasil