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Single-cell multi-omics defines the cell-type-specific impact of splicing aberrations in human hematopoietic clonal outgrowths.
Cortés-López, Mariela; Chamely, Paulina; Hawkins, Allegra G; Stanley, Robert F; Swett, Ariel D; Ganesan, Saravanan; Mouhieddine, Tarek H; Dai, Xiaoguang; Kluegel, Lloyd; Chen, Celine; Batta, Kiran; Furer, Nili; Vedula, Rahul S; Beaulaurier, John; Drong, Alexander W; Hickey, Scott; Dusaj, Neville; Mullokandov, Gavriel; Stasiw, Adam M; Su, Jiayu; Chaligné, Ronan; Juul, Sissel; Harrington, Eoghan; Knowles, David A; Potenski, Catherine J; Wiseman, Daniel H; Tanay, Amos; Shlush, Liran; Lindsley, Robert C; Ghobrial, Irene M; Taylor, Justin; Abdel-Wahab, Omar; Gaiti, Federico; Landau, Dan A.
Afiliação
  • Cortés-López M; New York Genome Center, New York, NY, USA; Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Chamely P; New York Genome Center, New York, NY, USA; Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Hawkins AG; Childhood Cancer Data Lab, Alex's Lemonade Stand Foundation, Philadelphia, PA, USA.
  • Stanley RF; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Swett AD; New York Genome Center, New York, NY, USA; Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Ganesan S; New York Genome Center, New York, NY, USA; Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Mouhieddine TH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Dai X; Oxford Nanopore Technologies Inc., New York, NY, USA.
  • Kluegel L; New York Genome Center, New York, NY, USA; Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Chen C; New York Genome Center, New York, NY, USA; Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Tri-Institutional MD-PhD Program, Weill Cornell Medicine, Rockefeller University, Memorial Sloan Kettering Cancer Center,
  • Batta K; Division of Cancer Sciences, The University of Manchester, Manchester, UK.
  • Furer N; Weizmann Institute of Science, Department of Molecular Cell Biology, Rehovot, Israel.
  • Vedula RS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Beaulaurier J; Oxford Nanopore Technologies Inc., San Francisco, CA, USA.
  • Drong AW; Oxford Nanopore Technologies Inc., New York, NY, USA.
  • Hickey S; Oxford Nanopore Technologies Inc., San Francisco, CA, USA.
  • Dusaj N; New York Genome Center, New York, NY, USA; Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Tri-Institutional MD-PhD Program, Weill Cornell Medicine, Rockefeller University, Memorial Sloan Kettering Cancer Center,
  • Mullokandov G; New York Genome Center, New York, NY, USA; Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Stasiw AM; New York Genome Center, New York, NY, USA; Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Su J; New York Genome Center, New York, NY, USA; Department of Systems Biology, Columbia University, New York, NY, USA.
  • Chaligné R; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Juul S; Oxford Nanopore Technologies Inc., New York, NY, USA.
  • Harrington E; Oxford Nanopore Technologies Inc., New York, NY, USA.
  • Knowles DA; New York Genome Center, New York, NY, USA; Department of Systems Biology, Columbia University, New York, NY, USA; Department of Computer Science, Columbia University, New York, NY, USA.
  • Potenski CJ; New York Genome Center, New York, NY, USA; Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.
  • Wiseman DH; Division of Cancer Sciences, The University of Manchester, Manchester, UK.
  • Tanay A; Weizmann Institute of Science, Department of Computer Science and Applied Mathematics, Rehovot, Israel.
  • Shlush L; Weizmann Institute of Science, Department of Molecular Cell Biology, Rehovot, Israel.
  • Lindsley RC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Ghobrial IM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Taylor J; Sylvester Comprehensive Cancer Center, University of Miami, Miller School of Medicine, Miami, FL, USA.
  • Abdel-Wahab O; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Gaiti F; University Health Network, Princess Margaret Cancer Centre, Toronto, ON, Canada; University of Toronto, Medical Biophysics, Toronto, ON, Canada. Electronic address: federico.gaiti@uhn.ca.
  • Landau DA; New York Genome Center, New York, NY, USA; Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA. Electronic address: dlandau@nygenome.
Cell Stem Cell ; 30(9): 1262-1281.e8, 2023 09 07.
Article em En | MEDLINE | ID: mdl-37582363
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Sítios de Splice de RNA Limite: Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Sítios de Splice de RNA Limite: Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos