Location bias: A "Hidden Variable" in GPCR pharmacology.

Eiger, Dylan Scott; Hicks, Chloe; Gardner, Julia; Pham, Uyen; Rajagopal, Sudarshan

Eiger, Dylan Scott; Hicks, Chloe; Gardner, Julia; Pham, Uyen; Rajagopal, Sudarshan.

Afiliação

Eiger DS; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Hicks C; Harvard Medical School, Boston, Massachusetts, USA.
Gardner J; Trinity College, Duke University, Durham, North Carolina, USA.
Pham U; Trinity College, Duke University, Durham, North Carolina, USA.
Rajagopal S; Department of Biochemistry, Duke University, Durham, North Carolina, USA.

Bioessays ; 45(11): e2300123, 2023 Nov.

Article em En | MEDLINE | ID: mdl-37625014

Palavras-chave

G protein-coupled receptor; G proteins; biased agonism; location bias; subcellular signaling; ß-arrestin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Bioessays Assunto da revista: BIOLOGIA / BIOLOGIA MOLECULAR Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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