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Modeling of the human interleukin 12:receptor complex allows to engineer attenuated cytokine variants.
Liebl, Korbinian; Aschenbrenner, Isabel; Schiller, Lisa; Kerle, Anna; Protzer, Ulrike; Feige, Matthias J.
Afiliação
  • Liebl K; Center for Functional Protein Assemblies (CPA), Department of Bioscience, TUM School of Natural Sciences, Technical University of Munich, 85748 Garching, Germany.
  • Aschenbrenner I; Center for Functional Protein Assemblies (CPA), Department of Bioscience, TUM School of Natural Sciences, Technical University of Munich, 85748 Garching, Germany.
  • Schiller L; Institute of Virology, TUM School of Medicine, Technical University of Munich/Helmholtz Munich, 81675 Munich, Germany.
  • Kerle A; Center for Functional Protein Assemblies (CPA), Department of Bioscience, TUM School of Natural Sciences, Technical University of Munich, 85748 Garching, Germany.
  • Protzer U; Institute of Virology, TUM School of Medicine, Technical University of Munich/Helmholtz Munich, 81675 Munich, Germany. Electronic address: protzer@tum.de.
  • Feige MJ; Center for Functional Protein Assemblies (CPA), Department of Bioscience, TUM School of Natural Sciences, Technical University of Munich, 85748 Garching, Germany. Electronic address: matthias.feige@tum.de.
Mol Immunol ; 162: 38-44, 2023 10.
Article em En | MEDLINE | ID: mdl-37639747

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-12 / Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Immunol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-12 / Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Immunol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha