miR-146a aggravates cognitive impairment and Alzheimer disease-like pathology by triggering oxidative stress through MAPK signaling.

Zhan-Qiang, H; Hai-Hua, Q; Chi, Z; Miao, W; Cui, Z; Zi-Yin, L; Jing, H; Yi-Wei, W

Zhan-Qiang, H; Hai-Hua, Q; Chi, Z; Miao, W; Cui, Z; Zi-Yin, L; Jing, H; Yi-Wei, W.

Afiliação

Zhan-Qiang H; Department of General medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China.
Hai-Hua Q; Department of Dermatology, Affiliated Hospital of Chengde Medical College, Chengde 067000, China.
Chi Z; Department of Neurology, Affilicated Hospital of Chengde Medical College, Chengde 067000, China.
Miao W; Department of General medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China.
Cui Z; Department of General medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China.
Zi-Yin L; Department of General medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China.
Jing H; Department of General medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China.
Yi-Wei W; Department of General medicine, Affiliated Hospital of Chengde Medical College, Chengde 067000, China. Electronic address: wangyiwei9511_cmc@163.com.

Neurologia (Engl Ed) ; 38(7): 486-494, 2023 Sep.

Article em En | MEDLINE | ID: mdl-37659839

Assuntos

Doença de Alzheimer; Disfunção Cognitiva; MicroRNAs; Neuroblastoma; Humanos; Animais; Camundongos; Doença de Alzheimer/genética; Peptídeos beta-Amiloides; Espécies Reativas de Oxigênio; Estresse Oxidativo; Precursor de Proteína beta-Amiloide; MicroRNAs/genética

Palavras-chave

Alzheimer disease; Amyloid-ß; Enfermedad de Alzheimer; Especies reactivas de oxígeno; MAPK signaling; Reactive oxygen species; Señalización MAPK; miR-146a-5p; ß-amiloide

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Doença de Alzheimer / Disfunção Cognitiva / Neuroblastoma Limite: Animals / Humans Idioma: En Revista: Neurologia (Engl Ed) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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