Patients with telomere biology disorders show context specific somatic mosaic states with high frequency of U2AF1 variants.
Am J Hematol
; 98(12): E357-E359, 2023 12.
Article
em En
| MEDLINE
| ID: mdl-37665761
ABSTRACT
Somatic mosaic states in telomere biology disorders are characterized by somatic variants in the spliceosome and DNA damage response and repair pathways. A likely maladaptive response to short telomeres that may lead to increased hematological cancer.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Telômero
/
Telomerase
Limite:
Humans
Idioma:
En
Revista:
Am J Hematol
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos