Design, synthesis, and anti-tumor activity of derivatives of ring A and C-28 of asiatic acid.

Yan-Qiu, Meng; Meng, Bei-Bei; Xu, Dong-Ping; Wang, Zhi-Qi; Li, Jin-Ming; Huang, Mei-Qi

Yan-Qiu, Meng; Meng, Bei-Bei; Xu, Dong-Ping; Wang, Zhi-Qi; Li, Jin-Ming; Huang, Mei-Qi.

Afiliação

Yan-Qiu M; Department of Pharmaceutical Engineering, Shenyang University of Chemical Technology, Shenyang 110142, China.
Meng BB; Department of Pharmaceutical Engineering, Shenyang University of Chemical Technology, Shenyang 110142, China.
Xu DP; Department of Pharmaceutical Engineering, Shenyang University of Chemical Technology, Shenyang 110142, China.
Wang ZQ; Department of Pharmaceutical Engineering, Shenyang University of Chemical Technology, Shenyang 110142, China.
Li JM; Department of Pharmaceutical Engineering, Shenyang University of Chemical Technology, Shenyang 110142, China.
Huang MQ; Department of Pharmaceutical Engineering, Shenyang University of Chemical Technology, Shenyang 110142, China.

J Asian Nat Prod Res ; 26(4): 497-509, 2024 Apr.

Article em En | MEDLINE | ID: mdl-37670663

Assuntos

Antineoplásicos; Triterpenos Pentacíclicos; Humanos; Antineoplásicos/química; Relação Estrutura-Atividade; Linhagem Celular Tumoral; Simulação de Acoplamento Molecular; Proliferação de Células; Desenho de Fármacos; Estrutura Molecular; Ensaios de Seleção de Medicamentos Antitumorais

Palavras-chave

Computer-aided drug design; anti-tumor activity; asiatic acid derivatives

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triterpenos Pentacíclicos / Antineoplásicos Limite: Humans Idioma: En Revista: J Asian Nat Prod Res Assunto da revista: BOTANICA / QUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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