Long-term intake of &#945;-glycerophosphocholine (GPC) suppresses microglial inflammation and blood-brain barrier (BBB) disruption and promotes neurogenesis in senescence-accelerated mice prone 8 (SAMP8).

Umino, Mitsuki; Okuda, Mayumi; Ohkubo, Takeshi; Fujii, Tsutomu; Matsubara, Kiminori

Long-term intake of α-glycerophosphocholine (GPC) suppresses microglial inflammation and blood-brain barrier (BBB) disruption and promotes neurogenesis in senescence-accelerated mice prone 8 (SAMP8).

Umino, Mitsuki; Okuda, Mayumi; Ohkubo, Takeshi; Fujii, Tsutomu; Matsubara, Kiminori.

Afiliação

Umino M; Department of Human Life Science Education, Graduate School of Humanities and Social Sciences, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.
Okuda M; Department of Human Life Science Education, Graduate School of Education, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.
Ohkubo T; Department of Health Nutrition, Sendai Shirayuri Women's College, Sehndai, Miyagi, Japan.
Fujii T; Faculty of Food and Agricultural Sciences, Fukushima University, Fukushima, Japan.
Matsubara K; Department of Human Life Science Education, Graduate School of Humanities and Social Sciences, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.

Biosci Biotechnol Biochem ; 87(12): 1537-1542, 2023 Nov 21.

Article em En | MEDLINE | ID: mdl-37723613

Assuntos

Barreira Hematoencefálica; Microglia; Camundongos; Animais; Encéfalo; Hipocampo; Inflamação; Neurogênese

Palavras-chave

aging; glycerophosphocholine; hippocampus; microglia; neurogenesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Microglia Limite: Animals Idioma: En Revista: Biosci Biotechnol Biochem Assunto da revista: BIOQUIMICA / BIOTECNOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

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