Ox-LDL promotes M1-like polarization of macrophages through the miR-21-5p/SKP2/EP300 pathway.

Wu, Jinlei; Liu, Tingting; Xie, Wenjie; Zhuo, Yufeng; Feng, Yanling

Wu, Jinlei; Liu, Tingting; Xie, Wenjie; Zhuo, Yufeng; Feng, Yanling.

Afiliação

Wu J; Department of Cardiology, He Xian Memorial Affiliated Hospital of Southern Medical University, Guangzhou, China.
Liu T; Department of Internal Medicine, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, China.
Xie W; Department of Cardiology, He Xian Memorial Affiliated Hospital of Southern Medical University, Guangzhou, China.
Zhuo Y; Department of Cardiology, He Xian Memorial Affiliated Hospital of Southern Medical University, Guangzhou, China.
Feng Y; Department of Cardiology, He Xian Memorial Affiliated Hospital of Southern Medical University, Guangzhou, China.

J Biochem Mol Toxicol ; 38(1): e23516, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37728154

Assuntos

Proteína HMGB1; MicroRNAs; Humanos; Proteína HMGB1/genética; Proteína HMGB1/metabolismo; Células Endoteliais/metabolismo; MicroRNAs/metabolismo; Lipoproteínas LDL/metabolismo; Macrófagos/metabolismo; Luciferases/metabolismo; Apoptose; Células Endoteliais da Veia Umbilical Humana/metabolismo; Proliferação de Células; Proteína p300 Associada a E1A/metabolismo

Palavras-chave

M1-like polarization; atherosclerosis; miRNA; ox-LDL; protein-protein interaction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína HMGB1 / MicroRNAs Limite: Humans Idioma: En Revista: J Biochem Mol Toxicol Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA / TOXICOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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