Neurotropin alleviates cognitive impairment by inhibiting TLR4/MyD88/NF-&#954;B inflammation signaling pathway in mice with vascular dementia.

Zou, Huihui; Chen, Xinrun; Lu, Jiancong; Zhou, Wanfei; Zou, Xiaopei; Wu, Heyong; Li, Zhou; Zhou, Xianju

Neurotropin alleviates cognitive impairment by inhibiting TLR4/MyD88/NF-κB inflammation signaling pathway in mice with vascular dementia.

Zou, Huihui; Chen, Xinrun; Lu, Jiancong; Zhou, Wanfei; Zou, Xiaopei; Wu, Heyong; Li, Zhou; Zhou, Xianju.

Afiliação

Zou H; Special Medical Service Center, Neuroscience Center, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, China.
Chen X; Department of Neurology, General Hospital of Southern Theater Command, Chinese People's Liberation Army, Guangzhou, China.
Lu J; Special Medical Service Center, Neuroscience Center, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, China.
Zhou W; Special Medical Service Center, Neuroscience Center, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, China.
Zou X; Special Medical Service Center, Neuroscience Center, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, China.
Wu H; Special Medical Service Center, Neuroscience Center, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, China.
Li Z; Department of Intensive Care Unit, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, China. Electronic address: bravehearter@126.com.
Zhou X; Special Medical Service Center, Neuroscience Center, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, China. Electronic address: xianjuzhou2022@163.com.

Neurochem Int ; 171: 105625, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37774797

Assuntos

Disfunção Cognitiva; Demência Vascular; Camundongos; Animais; NF-kappa B/metabolismo; Fator 88 de Diferenciação Mieloide/metabolismo; Fator 88 de Diferenciação Mieloide/farmacologia; Receptor 4 Toll-Like/metabolismo; Demência Vascular/tratamento farmacológico; Transdução de Sinais; Inflamação/tratamento farmacológico; Disfunção Cognitiva/tratamento farmacológico; Disfunção Cognitiva/metabolismo

Palavras-chave

Bilateral common carotid artery stenosis; Memory impairment; NF-κB; Neuroinflammation; Neurotropin; TLR4; Vascular dementia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Demência Vascular / Disfunção Cognitiva Limite: Animals Idioma: En Revista: Neurochem Int Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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