Rapid screening, isolation, and activity evaluation of potential xanthine oxidase inhibitors in Polyporus umbellatus and mechanism of action in the treatment of gout.

Liu, Qiang; Zhuang, Siyuan; Li, Sainan; Nong, Yuyu; Zhang, Yutong; Liang, Jiaqi; Zhang, Yuchi; Liu, Chunming

Liu, Qiang; Zhuang, Siyuan; Li, Sainan; Nong, Yuyu; Zhang, Yutong; Liang, Jiaqi; Zhang, Yuchi; Liu, Chunming.

Afiliação

Liu Q; Central Laboratory, Changchun Normal University, Changchun, China.
Zhuang S; Central Laboratory, Changchun Normal University, Changchun, China.
Li S; Central Laboratory, Changchun Normal University, Changchun, China.
Nong Y; Central Laboratory, Changchun Normal University, Changchun, China.
Zhang Y; Central Laboratory, Changchun Normal University, Changchun, China.
Liang J; Central Laboratory, Changchun Normal University, Changchun, China.
Zhang Y; Central Laboratory, Changchun Normal University, Changchun, China.
Liu C; Central Laboratory, Changchun Normal University, Changchun, China.

Phytochem Anal ; 35(1): 116-134, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37798938

Assuntos

Polyporus; Xantina Oxidase; Simulação de Acoplamento Molecular; Polyporus/química; Inibidores Enzimáticos/farmacologia

Palavras-chave

BP neural network genetic algorithm; Polyporus umbellatus; consecutive HSCCC and UNIFAC mathematical model; molecular docking technique and network pharmacology; xanthine oxidase inhibitors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Xantina Oxidase / Polyporus Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: Phytochem Anal Assunto da revista: BOTANICA / QUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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