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Repurposing the FDA-approved anthelmintic pyrvinium pamoate for pancreatic cancer treatment: study protocol for a phase I clinical trial in early-stage pancreatic ductal adenocarcinoma.
Ponzini, Francesca M; Schultz, Christopher W; Leiby, Benjamin E; Cannaday, Shawnna; Yeo, T; Posey, James; Bowne, Wilbur B; Yeo, Charles; Brody, Jonathan R; Lavu, Harish; Nevler, Avinoam.
Afiliação
  • Ponzini FM; Department of Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Schultz CW; Center for Cancer Research, National Institutes of Health, Bethesda, Maryland, USA.
  • Leiby BE; Sidney Kimmel Medical College, Department of Pharmacology and Experimental Therapeutics, Division of Biostatistics, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Cannaday S; Department of Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Yeo T; Department of Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Posey J; Jefferson Pancreatic, Biliary and Related Cancer Center, Sidney Kimmel Cancer Center, Philadelphia, Pennsylvania, USA.
  • Bowne WB; Jefferson Pancreatic, Biliary and Related Cancer Center, Sidney Kimmel Cancer Center, Philadelphia, Pennsylvania, USA.
  • Yeo C; Department of Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Brody JR; Department of Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Lavu H; Jefferson Pancreatic, Biliary and Related Cancer Center, Sidney Kimmel Cancer Center, Philadelphia, Pennsylvania, USA.
  • Nevler A; Department of Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
BMJ Open ; 13(10): e073839, 2023 10 17.
Article em En | MEDLINE | ID: mdl-37848297
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Adenocarcinoma / Carcinoma Ductal Pancreático / Anti-Helmínticos Limite: Humans Idioma: En Revista: BMJ Open Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Adenocarcinoma / Carcinoma Ductal Pancreático / Anti-Helmínticos Limite: Humans Idioma: En Revista: BMJ Open Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos