Your browser doesn't support javascript.
loading
Far-red BODIPY-based oxime esters: photo-uncaging and drug delivery.
Wan, Zhaoxiong; Yu, Shupei; Wang, Qi; Sambath, Karthik; Harty, Roshena; Liu, Xiangshan; Chen, Hao; Wang, Chen; Liu, Xuan; Zhang, Yuanwei.
Afiliação
  • Wan Z; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, 323 Martin Luther King Jr. Blvd., Newark, New Jersey 07102, USA. yuanwei.zhang@njit.edu.
  • Yu S; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, 323 Martin Luther King Jr. Blvd., Newark, New Jersey 07102, USA. yuanwei.zhang@njit.edu.
  • Wang Q; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, 323 Martin Luther King Jr. Blvd., Newark, New Jersey 07102, USA. yuanwei.zhang@njit.edu.
  • Sambath K; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, 323 Martin Luther King Jr. Blvd., Newark, New Jersey 07102, USA. yuanwei.zhang@njit.edu.
  • Harty R; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, 323 Martin Luther King Jr. Blvd., Newark, New Jersey 07102, USA. yuanwei.zhang@njit.edu.
  • Liu X; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, 323 Martin Luther King Jr. Blvd., Newark, New Jersey 07102, USA. yuanwei.zhang@njit.edu.
  • Chen H; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, 323 Martin Luther King Jr. Blvd., Newark, New Jersey 07102, USA. yuanwei.zhang@njit.edu.
  • Wang C; Department of Chemistry and Biochemistry, Queens College, City University of New York, 65-30 Kissena Blvd., New York 11432, USA.
  • Liu X; Department of Electrical and Computer Engineering, New Jersey Institute of Technology, 323 Martin Luther King Jr. Blvd., Newark, New Jersey 07102, USA.
  • Zhang Y; Department of Chemistry and Environmental Science, College of Science and Liberal Arts, New Jersey Institute of Technology, 323 Martin Luther King Jr. Blvd., Newark, New Jersey 07102, USA. yuanwei.zhang@njit.edu.
J Mater Chem B ; 11(41): 9889-9893, 2023 10 25.
Article em En | MEDLINE | ID: mdl-37850246
Far-red BODIPY-based oxime esters for photo-uncaging were designed to release molecules of interest with carboxylic acids. The low power red LED light breaks the N-O oxime ester bond and frees the caged molecules. We studied the mechanism and kinetics of the uncaging procedure using a 1H NMR spectrometer. Moreover, the drug delivery strategy to release valproic acid (VPA) on demand was tested in vitro using this far-red BODIPY photo-uncaging strategy to induce apoptosis in tumor cells.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oximas / Ésteres Idioma: En Revista: J Mater Chem B Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oximas / Ésteres Idioma: En Revista: J Mater Chem B Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos