The Key Role of Astrocytes in Amyotrophic Lateral Sclerosis and Their Commitment to Glutamate Excitotoxicity.

Provenzano, Francesca; Torazza, Carola; Bonifacino, Tiziana; Bonanno, Giambattista; Milanese, Marco

Provenzano, Francesca; Torazza, Carola; Bonifacino, Tiziana; Bonanno, Giambattista; Milanese, Marco.

Afiliação

Provenzano F; Department of Pharmacy (DIFAR), University of Genoa, 16148 Genova, Italy.
Torazza C; Department of Pharmacy (DIFAR), University of Genoa, 16148 Genova, Italy.
Bonifacino T; Department of Pharmacy (DIFAR), University of Genoa, 16148 Genova, Italy.
Bonanno G; Inter-University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), 56122 Pisa, Italy.
Milanese M; Department of Pharmacy (DIFAR), University of Genoa, 16148 Genova, Italy.

Int J Mol Sci ; 24(20)2023 Oct 21.

Article em En | MEDLINE | ID: mdl-37895110

Assuntos

Esclerose Lateral Amiotrófica; Humanos; Esclerose Lateral Amiotrófica/metabolismo; Ácido Glutâmico/metabolismo; Astrócitos/metabolismo; Neuroglia/metabolismo; Neurônios/metabolismo

Palavras-chave

amyotrophic lateral sclerosis; astrocytes; autophagy; energy metabolism; glutamate excitotoxicity; glutamate release; mitochondria dysfunction; neuroinflammation; oxidative stress

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esclerose Lateral Amiotrófica Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Itália

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