FOXO3-Activated HOTTIP Sequesters miR-615-3p away from COL2A1 to Mitigate Intervertebral Disc Degeneration.

Hao, Yingjie; Zhu, Guangduo; Yu, Lei; Ren, Zhinan; Zhou, Weiwei; Zhang, Panke; Lian, Xu

Hao, Yingjie; Zhu, Guangduo; Yu, Lei; Ren, Zhinan; Zhou, Weiwei; Zhang, Panke; Lian, Xu.

Afiliação

Hao Y; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. Electronic address: haojack77@126.com.
Zhu G; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yu L; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Ren Z; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhou W; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhang P; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Lian X; Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Am J Pathol ; 194(2): 280-295, 2024 Feb.

Article em En | MEDLINE | ID: mdl-37981220

Assuntos

Degeneração do Disco Intervertebral; Disco Intervertebral; MicroRNAs; Núcleo Pulposo; Camundongos; Animais; Degeneração do Disco Intervertebral/genética; Degeneração do Disco Intervertebral/metabolismo; MicroRNAs/genética; MicroRNAs/metabolismo; Regulação da Expressão Gênica; Núcleo Pulposo/metabolismo; RNA Mensageiro/metabolismo; Apoptose/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Degeneração do Disco Intervertebral / Núcleo Pulposo / Disco Intervertebral Limite: Animals Idioma: En Revista: Am J Pathol Ano de publicação: 2024 Tipo de documento: Article

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