Melatonin inhibits the formation of chemically induced experimental encapsulating peritoneal sclerosis through modulation of T cell differentiation by suppressing of NF-&#954;B activation in dendritic cells.

Huang, Shing-Hwa; Hong, Zhi-Jie; Chen, Mei-Fei; Tsai, Meng-Wei; Chen, Shyi-Jou; Cheng, Chia-Pi; Sytwu, Huey-Kang; Lin, Gu-Jiun

Melatonin inhibits the formation of chemically induced experimental encapsulating peritoneal sclerosis through modulation of T cell differentiation by suppressing of NF-κB activation in dendritic cells.

Huang, Shing-Hwa; Hong, Zhi-Jie; Chen, Mei-Fei; Tsai, Meng-Wei; Chen, Shyi-Jou; Cheng, Chia-Pi; Sytwu, Huey-Kang; Lin, Gu-Jiun.

Afiliação

Huang SH; Department of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan; Department of General Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; Department of General Surgery, En Chu Kong Hospital, New Taipei, Taiwan.
Hong ZJ; Department of General Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan.
Chen MF; Department of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan.
Tsai MW; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.
Chen SJ; Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan.
Cheng CP; Department of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan.
Sytwu HK; Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan; National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Miaoli County, Taiwan.
Lin GJ; Department of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan; Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan. Electronic address: lingujiun@mail.ndmctsgh.edu.tw.

Int Immunopharmacol ; 126: 111300, 2024 Jan 05.

Article em En | MEDLINE | ID: mdl-38016346

Assuntos

Obstrução Intestinal; Melatonina; Fibrose Peritoneal; Humanos; Animais; Camundongos; Fibrose Peritoneal/etiologia; NF-kappa B/metabolismo; Melatonina/farmacologia; Melatonina/uso terapêutico; Diferenciação Celular; Transdução de Sinais; Células Dendríticas/metabolismo; Obstrução Intestinal/complicações; Obstrução Intestinal/patologia

Palavras-chave

Dendritic cell; Encapsulating peritoneal sclerosis; Melatonin; NF-κB; Peritoneal dialysis; Regulatory T cell; Th1; Th17

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose Peritoneal / Obstrução Intestinal / Melatonina Limite: Animals / Humans Idioma: En Revista: Int Immunopharmacol Assunto da revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Taiwan

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