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X-ray generation by fs-laser processing of biological material.
Mosel, P; Düsing, J; Johannesmeier, S; Patzlaff-Günther, M; Fröhlich, S; Mapa, J; Kalies, S; Bahlmann, J; Püster, T; Vahlbruch, J; Dittmar, G; Merdji, H; Fajardo, M; Trabattoni, A; Heisterkamp, A; Morgner, U; Kovacev, M.
Afiliação
  • Mosel P; Leibniz University Hannover, Welfengarten 1, Hannover 30167, Germany.
  • Düsing J; Laser Zentrum Hannover e.V., Hannover 30419, Germany.
  • Johannesmeier S; Laser Zentrum Hannover e.V., Hannover 30419, Germany.
  • Patzlaff-Günther M; Laser Zentrum Hannover e.V., Hannover 30419, Germany.
  • Fröhlich S; Leibniz University Hannover, Welfengarten 1, Hannover 30167, Germany.
  • Mapa J; Leibniz University Hannover, Welfengarten 1, Hannover 30167, Germany.
  • Kalies S; Leibniz University Hannover, Welfengarten 1, Hannover 30167, Germany.
  • Bahlmann J; Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), 30625 Hannover, Germany.
  • Püster T; Leibniz University Hannover, Welfengarten 1, Hannover 30167, Germany.
  • Vahlbruch J; Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), 30625 Hannover, Germany.
  • Dittmar G; Laser Zentrum Hannover e.V., Hannover 30419, Germany.
  • Merdji H; Institute of Radioecology and Radiation Protection, Leibniz University Hannover, Hannover 30419, Germany.
  • Fajardo M; Ingenieur-Büro Prof. Dr.-Ing. G. Dittmar, Aalen 73433, Germany.
  • Trabattoni A; LOA, ENSTA ParisTech, CNRS, Ecole Polytechnique, Université Paris-Saclay 828 Boulevard des Maréchaux, 91120, Palaiseau, France.
  • Heisterkamp A; GoLP, Instituto de Plasmas e Fusão Nuclear, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.
  • Morgner U; Leibniz University Hannover, Welfengarten 1, Hannover 30167, Germany.
  • Kovacev M; Center for Free-Electron Laser Science CFEL, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Biomed Opt Express ; 14(11): 5656-5669, 2023 Nov 01.
Article em En | MEDLINE | ID: mdl-38021146
ABSTRACT
The use of ultrashort pulse lasers in medical treatments is increasing and is already an essential tool, particularly in the treatment of eyes, bones and skin. One of the main advantages of laser treatment is that it is fast and minimally invasive. Due to the interaction of ultrashort laser pulses with matter, X-rays can be generated during the laser ablation process. This is important not only for the safety of the patient, but also for the practitioner to ensure that the legally permissible dose is not exceeded. Although our results do not raise safety concerns for existing clinical applications, they might impact future developments at higher peak powers. In order to provide guidance to laser users in the medical field, this paper examines the X-ray emission spectra and dose of several biological materials and describes their dependence on the laser pulse energy.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biomed Opt Express Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biomed Opt Express Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha