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Blood-stage antimalarial activity, favourable metabolic stability and in vivo toxicity of novel piperazine linked 7-chloroquinoline-triazole conjugates.
Uddin, Amad; Gupta, Sonal; Shoaib, Rumaisha; Aneja, Babita; Irfan, Iram; Gupta, Kanika; Rawat, Neha; Combrinck, Jill; Kumar, Bhumika; Aleem, Mohd; Hasan, Phool; Joshi, Mukesh C; Chhonker, Yashpal S; Zahid, Muhammad; Hussain, Afzal; Pandey, Kailash; Alajmi, Mohamed F; Murry, Daryl J; Egan, Timothy J; Singh, Shailja; Abid, Mohammad.
Afiliação
  • Uddin A; Medicinal Chemistry Laboratory, Department of Biosciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India.
  • Gupta S; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India.
  • Shoaib R; Medicinal Chemistry Laboratory, Department of Biosciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India.
  • Aneja B; Medicinal Chemistry Laboratory, Department of Biosciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India.
  • Irfan I; Medicinal Chemistry Laboratory, Department of Biosciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India.
  • Gupta K; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India.
  • Rawat N; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India.
  • Combrinck J; Department of Chemistry, University of Cape Town, Private Bag, Rondebosch, Cape Town, 7701, South Africa.
  • Kumar B; Medicinal Chemistry Laboratory, Department of Biosciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India; National Institute of Malaria Research, New Delhi, 110077, India.
  • Aleem M; Division of Behavioral Neuroscience, Institute of Nuclear Medicine and Allied Sciences, Delhi, 110054, India.
  • Hasan P; Medicinal Chemistry Laboratory, Department of Biosciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India.
  • Joshi MC; Department of Chemistry, Kirori Mal College, University of Delhi, Delhi, 110007, India.
  • Chhonker YS; Department of Pharmacy Practice and Science College of Pharmacy, University of Nebraska Medical Center, 986145, Nebraska Medical Center, Omaha, NE, 68198-6145, USA.
  • Zahid M; Department of Environmental, Agricultural and Occupational Health, University of Nebraska Medical Center, 986145, Nebraska Medical Center, Omaha, NE, 68198-6145, USA.
  • Hussain A; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
  • Pandey K; National Institute of Malaria Research, New Delhi, 110077, India.
  • Alajmi MF; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
  • Murry DJ; Department of Pharmacy Practice and Science College of Pharmacy, University of Nebraska Medical Center, 986145, Nebraska Medical Center, Omaha, NE, 68198-6145, USA.
  • Egan TJ; Department of Chemistry, University of Cape Town, Private Bag, Rondebosch, Cape Town, 7701, South Africa.
  • Singh S; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India. Electronic address: shailja.jnu@gmail.com.
  • Abid M; Medicinal Chemistry Laboratory, Department of Biosciences, Jamia Millia Islamia, Jamia Nagar, New Delhi, 110025, India. Electronic address: mabid@jmi.ac.in.
Eur J Med Chem ; 264: 115969, 2024 Jan 15.
Article em En | MEDLINE | ID: mdl-38039787
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Malária / Antimaláricos Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Índia
Texto completo
Imprimir
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Malária / Antimaláricos Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Índia