A quantitative pharmacology model for cannabinoid CB<sub>1</sub> receptor mediated by Gi/Gs protein competition.

Yang, Liang; Finlay, David B; Green, Hayley M; Zhu, Xiao; Glass, Michelle; Duffull, Stephen

A quantitative pharmacology model for cannabinoid CB₁ receptor mediated by Gi/Gs protein competition.

Yang, Liang; Finlay, David B; Green, Hayley M; Zhu, Xiao; Glass, Michelle; Duffull, Stephen.

Afiliação

Yang L; Otago Pharmacometrics Group, School of Pharmacy, University of Otago, Dunedin, New Zealand.
Finlay DB; Department of Pharmacology and Toxicology, University of Otago, Dunedin, New Zealand.
Green HM; Department of Pharmacology and Toxicology, University of Otago, Dunedin, New Zealand.
Zhu X; Department of Clinical Pharmacy and Pharmacy Administration, School of Pharmacy, Fudan University, Shanghai, China.
Glass M; Department of Pharmacology and Toxicology, University of Otago, Dunedin, New Zealand.
Duffull S; Otago Pharmacometrics Group, School of Pharmacy, University of Otago, Dunedin, New Zealand.

Br J Pharmacol ; 181(8): 1324-1340, 2024 Apr.

Article em En | MEDLINE | ID: mdl-38072805

Assuntos

Canabinoides; Proteínas de Ligação ao GTP; Receptores de Canabinoides/metabolismo; Proteínas de Ligação ao GTP/metabolismo; Transdução de Sinais; Canabinoides/farmacologia; Receptor CB1 de Canabinoide/metabolismo; Receptor CB2 de Canabinoide/metabolismo

Palavras-chave

CB1 receptor; G protein; cyclic AMP; mathematical model

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canabinoides / Proteínas de Ligação ao GTP Idioma: En Revista: Br J Pharmacol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Nova Zelândia

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