Optimizing dose-schedule regimens with bayesian adaptive designs: opportunities and challenges.

Chen, Xin; He, Ruyue; Chen, Xinyi; Jiang, Liyun; Wang, Fei

Chen, Xin; He, Ruyue; Chen, Xinyi; Jiang, Liyun; Wang, Fei.

Afiliação

Chen X; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, China.
He R; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, China.
Chen X; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, China.
Jiang L; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, China.
Wang F; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, China.

Front Pharmacol ; 14: 1261312, 2023.

Article em En | MEDLINE | ID: mdl-38074141

Palavras-chave

adaptive design; bayesian method; dosage optimization; dose-schedule regimen; early phase clinical trial

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Pharmacol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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