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Seroreversion to Chlamydia trachomatis Pgp3 Antigen Among Children in a Hyperendemic Region of Amhara, Ethiopia.
Tedijanto, Christine; Aragie, Solomon; Gwyn, Sarah; Wittberg, Dionna M; Zeru, Taye; Tadesse, Zerihun; Chernet, Ambahun; Thompson, Isabel J B; Nash, Scott D; Lietman, Thomas M; Martin, Diana L; Keenan, Jeremy D; Arnold, Benjamin F.
Afiliação
  • Tedijanto C; Francis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, USA.
  • Aragie S; The Carter Center Ethiopia, Addis Ababa, Ethiopia.
  • Gwyn S; Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Wittberg DM; Francis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, USA.
  • Zeru T; Amhara Public Health Institute, Bahir Dar, Ethiopia.
  • Tadesse Z; The Carter Center Ethiopia, Addis Ababa, Ethiopia.
  • Chernet A; The Carter Center Ethiopia, Addis Ababa, Ethiopia.
  • Thompson IJB; Francis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, USA.
  • Nash SD; The Carter Center, Atlanta, Georgia, USA.
  • Lietman TM; Francis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, USA.
  • Martin DL; Department of Ophthalmology, University of California, San Francisco, San Francisco, California, USA.
  • Keenan JD; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA.
  • Arnold BF; Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
J Infect Dis ; 230(2): 293-297, 2024 Aug 16.
Article em En | MEDLINE | ID: mdl-38134305
ABSTRACT
Monitoring trachoma transmission with antibody data requires characterization of decay in IgG to Chlamydia trachomatis antigens. In a 3-year longitudinal cohort in a high-transmission setting, we estimated a median IgG half-life of 3 years and a seroreversion rate of 2.5 per 100 person-years (95% confidence interval, 1.6-3.5). Clinical Trials Registration NCT02754583.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Imunoglobulina G / Chlamydia trachomatis / Tracoma / Anticorpos Antibacterianos / Antígenos de Bactérias Limite: Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Africa Idioma: En Revista: J Infect Dis Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Imunoglobulina G / Chlamydia trachomatis / Tracoma / Anticorpos Antibacterianos / Antígenos de Bactérias Limite: Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Africa Idioma: En Revista: J Infect Dis Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos