A study of the effect of hypothyroidism during pregnancy on human milk quality based on rheological properties.
J Dairy Sci
; 107(6): 3400-3412, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38135045
ABSTRACT
Hypothyroidism has been found to have an effect on the nutritional composition of human milk during pregnancy. This study aims to explore the combined influence of rheological properties, macronutrient content, particle size, and the zeta potential of milk fat globules, as well as the composition of milk fat globule membrane (MFGM) proteins on the quality of human milk in gestational hypothyroidism. The study revealed that human milk from the group with hypothyroidism during pregnancy (AHM) was less viscoelastic and stable when compared with normal pregnancy group human milk (NHM). Furthermore, the particle size and macronutrient content of NHM were found to be larger than that of AHM. In contrast, the zeta potential of AHM was greater than that of NHM. The sodium dodecyl sulfate-PAGE results disclosed that the composition of MFGM proteins in these 2 groups were generally the same, but the content of AHM was lower than that of NHM. In conclusion, this study confirms that hypothyroidism during pregnancy can have a significant effect on the quality of human milk.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Reologia
/
Hipotireoidismo
/
Leite Humano
Limite:
Female
/
Humans
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Pregnancy
Idioma:
En
Revista:
J Dairy Sci
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China