Percutaneous cryoablation of symptomatic uterine adenomyomas: Initial experience.
J Gynecol Obstet Hum Reprod
; 53(3): 102727, 2024 Mar.
Article
em En
| MEDLINE
| ID: mdl-38237806
ABSTRACT
OBJECTIVE:
To assess the efficacy and safety of percutaneous image-guided cryoablation of adenomyomas MATERIAL ANDMETHODS:
Five symptomatic women who wanted to preserve their uterus and fertility underwent a single session of percutaneous image-guided cryoablation of adenomyoma. Three to six 17-gauge cryoprobes were introduced percutaneously into the adenomyoma under ultrasound and laparoscopy guidance. Clinical efficacy was defined as the diminution of the Visual Analogue Scale of pain (VAS), the decrease in uterine bleeding and the improvement of quality of life assessed by the endometriosis health profile 5 (EHP-5) 12 months after treatment. Technical efficacy was defined by the reduction in volume of each treated adenomyoma on MRI. Complications were classified using the Clavien-Dindo classification system. Hysterosonography was performed at least 3 months after the procedure.RESULTS:
Compared to the baseline, all symptom scores had decreased after 12 months median VAS 8/10 (range, 5-10) to 4/10 (range, 0-7); median dyspareunia score 7/10 (range, 0-10) to 2/10 (range, 0-8); median bleeding score 335 (range, 102-920) to 76 (range, 0-88); median EHP-5 score 60/100 (range, 50-75) to 50/100 (range, 32-55). The median volume of adenomyosis decreased from 57 cm3 (range, 8-87) to 9 cm3 (range, 2-45) at 12 months. No postoperative complications occurred. Two patients had incomplete intrauterine adhesions that were easily removed hysteroscopically.CONCLUSION:
Cryoablation may be a promising alternative treatment for symptomatic adenomyoma in women who want to preserve their uterus.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Uterinas
/
Adenomioma
/
Criocirurgia
/
Endometriose
Tipo de estudo:
Diagnostic_studies
/
Guideline
Limite:
Female
/
Humans
Idioma:
En
Revista:
J Gynecol Obstet Hum Reprod
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
França