Synthesis and Structural Characterization of Macrocyclic α-ABpeptoids and Their DNA-Encoded Library.
Org Lett
; 26(5): 1100-1104, 2024 02 09.
Article
em En
| MEDLINE
| ID: mdl-38295374
ABSTRACT
The first synthesis of macrocyclic α-ABpeptoids with varying lengths is described. X-ray crystal structures reveal that cyclic trimer displays a chair-like conformation with a cct amide sequence and cyclic tetramer has a saddle-like structure with an uncommon cccc amide arrangement. The creation of a DNA-encoded combinatorial library of macrocyclic α-ABpeptoids is described.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA
/
Peptoides
Idioma:
En
Revista:
Org Lett
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Coréia do Sul