[Determination of Perchloroethylene in blood by headspace gas chromatography-mass spectrometry].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
; 42(1): 42-46, 2024 Jan 20.
Article
em Zh
| MEDLINE
| ID: mdl-38311948
ABSTRACT
Objective:
To establish a method for determination of Perchloroethylene (PCE) in blood by headspace gas chromatography-mass spectrometry (HS/GC-MS) .Methods:
From Dctober to December 2021, A total of 3 mL blood samples were taken into a 10 mL headspace bottle, after heated at 60 â for 30 mins, PCE in the top air was separated by VF-WAXms capillary column and detected by GC-MS. The retention time and external standard method were used for qualitative and quantitative analysis of PCE in samples, respectively.Results:
There was good linear relationship in the range of 5.09-200.17 µg/L. The linear correlation coefficient was 0.9993.The detection limit was 0.21 µg/L and the lower limit of quantitation was 0.70 µg/L. The recovery rates of samples with different concentrations were 95.3%-103.8%. The intra-batch relative standard deviations (RSD) were 3.2%-4.6%, and inter-batch RSD was 4.0%-6.1%. The samples can be stored at 4 â for three days and at -20 â for seven days.Conclusion:
This method is proved to be simple, practical and highly sensitive, which is suitable for the determination of PCE in blood.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tetracloroetileno
Tipo de estudo:
Qualitative_research
Idioma:
Zh
Revista:
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
Assunto da revista:
MEDICINA OCUPACIONAL
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China