Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1.

Mycroft-West, Courtney J; Abdelkarim, Sahar; Duyvesteyn, Helen M E; Gandhi, Neha S; Skidmore, Mark A; Owens, Raymond J; Wu, Liang

Mycroft-West, Courtney J; Abdelkarim, Sahar; Duyvesteyn, Helen M E; Gandhi, Neha S; Skidmore, Mark A; Owens, Raymond J; Wu, Liang.

Afiliação

Mycroft-West CJ; The Rosalind Franklin Institute, Harwell Science & Innovation Campus, OX11 0QX, Didcot, UK.
Abdelkarim S; The Rosalind Franklin Institute, Harwell Science & Innovation Campus, OX11 0QX, Didcot, UK.
Duyvesteyn HME; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, OX3 7BN, Oxford, UK.
Gandhi NS; Department of Computer Science and Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.
Skidmore MA; School of Chemistry and Physics, Queensland University of Technology, QLD 4000, Brisbane, Australia.
Owens RJ; Centre for Genomics and Personalised Health, Queensland University of Technology, Brisbane, QLD 4059, Australia.
Wu L; Centre for Glycoscience Research and Training, Keele University, ST5 5BG, Newcastle-Under-Lyme, UK.

Nat Commun ; 15(1): 1326, 2024 Feb 13.

Article em En | MEDLINE | ID: mdl-38351061

Assuntos

Heparitina Sulfato; Sulfotransferases; Humanos; Microscopia Crioeletrônica; Heparitina Sulfato/metabolismo; Domínio Catalítico; Sulfotransferases/metabolismo; Matriz Extracelular/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfotransferases / Heparitina Sulfato Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Reino Unido

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