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Percutaneous tibial nerve stimulation versus sacral nerve stimulation for the treatment of faecal incontinence.
O'Connor, Alexander; Reynolds, Elizabeth; Molyneux, Clare; Vasant, Dipesh H; Sharma, Abhiram; Faulkner, Gemma; McLaughlin, John; Kiff, Edward; Telford, Karen.
Afiliação
  • O'Connor A; Department of Colorectal Surgery, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
  • Reynolds E; Faculty of Biology, Medicine, and Health, The University of Manchester, Manchester, United Kingdom.
  • Molyneux C; Department of Colorectal Surgery, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
  • Vasant DH; Department of Colorectal Surgery, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
  • Sharma A; Neurogastroenterology Unit, Gastroenterology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
  • Faulkner G; Division of Diabetes, Endocrinology and Gastroenterology, The University of Manchester, Manchester, United Kingdom.
  • McLaughlin J; Department of Colorectal Surgery, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
  • Kiff E; Faculty of Biology, Medicine, and Health, The University of Manchester, Manchester, United Kingdom.
  • Telford K; Department of Colorectal Surgery, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
Front Surg ; 11: 1303119, 2024.
Article em En | MEDLINE | ID: mdl-38357189
ABSTRACT

Introduction:

Faecal incontinence (FI) is a common condition with a significant impact on quality of life (QoL). Neuromodulation treatments delivered by members of the multidisciplinary team including sacral nerve stimulation (SNS) and percutaneous tibial nerve stimulation (PTNS) are options for FI refractory to conservative management. The aim of this study was to assess whether a successful treatment with one neuromodulation modality corresponds with success in the other.

Methods:

A retrospective review of a prospectively managed neuromodulation database identified 15 patients who had undergone both PTNS and SNS. The definition of success of each treatment was a >50% improvement in any of The St. Mark's Incontinence Score, Manchester Health Questionnaire, or weekly faecal urgency or FI episodes.

Results:

Complete data from 12 patients was available for assessment and PTNS was delivered as the first treatment in nine patients. Overall, seven patients (58%) had successful PTNS treatment, with 10 (83%) having a successful SNS trials. Of the seven patients who had successful PTNS treatment, six patients (85.4%) went on to have success with SNS. Of the five patients who failed PTNS, four (80%) went on to have SNS success. Five (71%) of those who had positive PTNS outcomes had permanent SNS implantation as their final treatment decision.

Conclusion:

This study suggests that there is no clear relationship between successful PTNS treatment and an SNS trial period which may be explained by differing mechanisms of action or the potential placebo effect of PTNS. Further work is required to investigate any association in larger studies to inform clinical practice.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Prognostic_studies Idioma: En Revista: Front Surg Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Prognostic_studies Idioma: En Revista: Front Surg Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Reino Unido