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Effect of romosozumab in premenopausal women with severe osteoporosis and anorexia nervosa.
Fujimoto, Kazuki; Maki, Narumi; Hashiba, Daisuke; Maeyama, Toshifumi; Nakagawa, Ryosuke; Arai, Hajime; Ohtori, Seiji.
Afiliação
  • Fujimoto K; Department of Orthopaedic Surgery, Kohnodai Hospital, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa City, Chiba, 272-8516, Japan.
  • Maki N; Department of Orthopaedic Surgery, Kohnodai Hospital, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa City, Chiba, 272-8516, Japan.
  • Hashiba D; Department of Orthopaedic Surgery, Kohnodai Hospital, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa City, Chiba, 272-8516, Japan.
  • Maeyama T; Department of Orthopaedic Surgery, Kohnodai Hospital, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa City, Chiba, 272-8516, Japan.
  • Nakagawa R; Department of Orthopaedic Surgery, Kohnodai Hospital, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa City, Chiba, 272-8516, Japan.
  • Arai H; Department of Orthopaedic Surgery, Kohnodai Hospital, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa City, Chiba, 272-8516, Japan.
  • Ohtori S; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan.
Osteoporos Sarcopenia ; 9(4): 137-141, 2023 Dec.
Article em En | MEDLINE | ID: mdl-38374824
ABSTRACT

Objectives:

This study aims to investigate the effects of romosozumab on bone mineral density (BMD) and bone metabolism.

Methods:

In this retrospective case series, romosozumab was administered to 5 premenopausal female patients with osteoporosis and anorexia nervosa with fragility fractures. BMD and bone turnover marker changes were investigated at 6 months and 1 year after administering romosozumab.

Results:

BMD increased and high-turnover bone metabolism decreased 6 months and 1 year after administering romosozumab.

Conclusions:

Romosozumab is useful for treating osteoporosis in patients with anorexia nervosa.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Osteoporos Sarcopenia Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Osteoporos Sarcopenia Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão