The HSP90 chaperone code regulates the crosstalk between proteostasis and autophagy.
Autophagy
; 20(7): 1689-1691, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38411135
ABSTRACT
Proteostasis, the maintenance of proper protein folding, stability, and degradation within cells, is fundamental for cellular function. Two key players in this intricate cellular process are macroautophagy/autophagy and chaperoning of nascent proteins. Here, we explore the crosstalk between autophagy and the HSP90 chaperone in maintaining proteostasis, highlighting their interplay and significance in cellular homeostasis.Abbreviation HSP90 heat shock protein 90; PTMs post-translational modifications.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Autofagia
/
Proteínas de Choque Térmico HSP90
/
Proteostase
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Autophagy
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos