Achievement of Dynamic Tablet Defect Detection Mechanism Using Biaxial Slope Symmetry Algorithm.
J Pharm Sci
; 2024 Mar 12.
Article
em En
| MEDLINE
| ID: mdl-38484876
ABSTRACT
An inspection in tablet appearance integrity before bottling is regarded as a routine task in a pharmaceutical factory. Although some methods such as automated optical instrument, video or artificial intelligence (AI) are currently available in industry, it usually pays for a complex computational process as well as high cost. Based on the symmetry of tablet appearance in reality, this study develops a biaxial scanning slope symmetry algorithm to realize a dynamic real-time tablet defect detection with a simple arithmetic operation. First, the tablet is discretely scanned using image sensor in two axes, i.e. X and Y directions, simultaneously. Second, the analogy output signals generated from the sensor during the scanning process is discretely digitized and stored in an array. Third, the coordinate of center point in the series data array is identified from every line scanning. Fourth, every section slope between two nearby center points from the first to last lines is formulated and calculated sequentially. Finally, the square mean error (SME) is used to evaluate the shape defect situation according to all accumulated errors from every slope variation. The experimental results verify that the proposed algorithm can achieve both fast and accurate detection performance.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Pharm Sci
Ano de publicação:
2024
Tipo de documento:
Article