Sex-specific effects of injury and beta-adrenergic activation on metabolic and inflammatory mediators in a murine model of post-traumatic osteoarthritis.

Komaravolu, Ravi K; Mehta-D'souza, Padmaja; Conner, Taylor; Allen, Madeline; Lumry, Jessica; Batushansky, Albert; Pezant, Nathan P; Montgomery, Courtney G; Griffin, Timothy M

Komaravolu, Ravi K; Mehta-D'souza, Padmaja; Conner, Taylor; Allen, Madeline; Lumry, Jessica; Batushansky, Albert; Pezant, Nathan P; Montgomery, Courtney G; Griffin, Timothy M.

Afiliação

Komaravolu RK; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. Electronic address: ravikumar.komaravolu@gmail.com.
Mehta-D'souza P; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. Electronic address: Padmaja-Mehta-Dsouza@omrf.org.
Conner T; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. Electronic address: Taylor-Conner@omrf.org.
Allen M; Department of Health and Exercise Science, University of Oklahoma, Norman, OK 73019, USA. Electronic address: madeline-allen@ouhsc.edu.
Lumry J; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. Electronic address: jessicalumry@gmail.com.
Batushansky A; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. Electronic address: albert.batushansky@gmail.com.
Pezant NP; Center for Biomedical Data Sciences, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. Electronic address: Nathan-Pezant@omrf.org.
Montgomery CG; Center for Biomedical Data Sciences, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. Electronic address: Courtney-Montgomery@omrf.org.
Griffin TM; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA; Oklahoma City VA Health Care System, Oklahoma City, OK 73104, USA; Oklahoma Center for Geroscience and the Department of Biochemistry and Molecular Biology, University of Oklahoma Health Scienc

Osteoarthritis Cartilage ; 32(9): 1097-1112, 2024 Sep.

Article em En | MEDLINE | ID: mdl-38527663

Assuntos

Agonistas Adrenérgicos beta; Isoproterenol; Animais; Feminino; Masculino; Camundongos; Isoproterenol/farmacologia; Agonistas Adrenérgicos beta/farmacologia; Modelos Animais de Doenças; Fatores Sexuais; Membrana Sinovial/metabolismo; Tecido Adiposo/metabolismo; Mediadores da Inflamação/metabolismo; Receptores Adrenérgicos beta/metabolismo; Injeções Intra-Articulares; Traumatismos do Joelho/complicações; Traumatismos do Joelho/metabolismo; Osteoartrite do Joelho/metabolismo; Osteoartrite do Joelho/etiologia; Cartilagem Articular/metabolismo; Cartilagem Articular/efeitos dos fármacos; Cartilagem Articular/patologia; Camundongos Endogâmicos C57BL

Palavras-chave

Infrapatellar fat pad; Lipids; Metabolomics; Sexual dimorphism; Synovial fluid

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Agonistas Adrenérgicos beta / Isoproterenol Limite: Animals Idioma: En Revista: Osteoarthritis Cartilage Assunto da revista: ORTOPEDIA / REUMATOLOGIA Ano de publicação: 2024 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google