Pre-pregnancy maternal obesity and infant neurodevelopmental outcomes in Latino infants.
Obesity (Silver Spring)
; 32(5): 979-988, 2024 05.
Article
em En
| MEDLINE
| ID: mdl-38600046
ABSTRACT
OBJECTIVE:
This study explores the impact of maternal pre-pregnancy BMI on infant neurodevelopment at 24 months in low-income Latino families. It also investigates whether infant diet mediates this relationship.METHODS:
Latino mother-infant pairs (n = 163) were enrolled at 1 month post partum and were followed for 2 years, with assessments at 6-month intervals. Maternal pre-pregnancy anthropometrics were self-reported at baseline, and child neurodevelopment was assessed at 24 months using the Bayley Scales of Infant Development. Diet quality of infants was measured using the Healthy Eating Index (HEI)-2015 and HEI-Toddlers-2020 scores at multiple time points. Mediation and regression models that adjust for maternal factors were used to examine the associations.RESULTS:
Pre-pregnancy BMI showed significant negative associations with child cognitive scores (ß = -0.1, 95% CI -0.2 to -0.06, p < 0.001) and language scores (ß = -0.1, 95% CI -0.2 to -0.03, p = 0.01) at 24 months. Infant HEI-2015 scores at 24 months partly mediated these associations, explaining 23% and 30% of the total effect on cognitive and language subscales, respectively. No specific dietary components in infants mediated the relationship, except for the total HEI-2015 score.CONCLUSIONS:
Managing maternal obesity pre-pregnancy is crucial for improving infant neurodevelopmental outcomes, especially in low-income Latino families. Promoting healthy weight and enhancing infant diet quality can enhance neurodevelopment in these populations.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hispânico ou Latino
/
Índice de Massa Corporal
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Desenvolvimento Infantil
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Obesidade Materna
Limite:
Adult
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Female
/
Humans
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Infant
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Male
/
Pregnancy
Idioma:
En
Revista:
Obesity (Silver Spring)
Assunto da revista:
CIENCIAS DA NUTRICAO
/
FISIOLOGIA
/
METABOLISMO
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos