Antibiotics-associated pseudomembranous colitis: a disproportionality analysis of the US food and drug administration adverse event reporting system (FAERS) database.
Expert Opin Drug Saf
; : 1-7, 2024 Apr 11.
Article
em En
| MEDLINE
| ID: mdl-38603461
ABSTRACT
BACKGROUND:
Evaluating antibiotics most commonly associated with pseudomembranous colitis (PMC) based on the real-world data is of great significance. RESEARCH DESIGN ANDMETHODS:
We used the data from FAERS to evaluate the potential association between antibiotics and PMC by disproportionality analyzes.RESULTS:
Eighty-one antibiotics which met the three algorithms simultaneously were enrolled. There were 1683 reports of PMC associated with the enrolled antibiotics. In the top 24 antibiotics, cefoxitin, streptomycin, fosfomycin, and micafungin had a high risk of PMC, but there were few reports in the literature.CONCLUSIONS:
This study was of great significance for healthcare professionals to realize the potential PMC risks of antibiotics.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Expert Opin Drug Saf
Assunto da revista:
FARMACOLOGIA
/
TERAPIA POR MEDICAMENTOS
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China