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Fragile hands: targeting nonmelanoma skin cancer on older hands using 595 nm pulsed dye laser.
Herron, Elliott D; Snyder, Ashley M; Hull, Christopher M; LoBello, Steven; Herron, Mark D.
Afiliação
  • Herron ED; Heersink School of Medicine, University of Alabama Birmingham, Birmingham, Alabama, United States.
  • Snyder AM; Department of Dermatology, University of Utah, Salt Lake City, Utah, United States.
  • Hull CM; Department of Population Health Sciences, University of Utah, Salt Lake City, Utah, United States.
  • LoBello S; Division of Epidemiology, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, United States.
  • Herron MD; Department of Dermatology, University of Utah, Salt Lake City, Utah, United States.
Lasers Med Sci ; 39(1): 101, 2024 Apr 17.
Article em En | MEDLINE | ID: mdl-38630146
ABSTRACT

PURPOSE:

The mainstay of treatment for nonmelanoma skin cancer (NMSC) on thin skin remains surgical, but procedures on older hands may be complicated by skin fragility and dermal atrophy. Used without cooling, 595 nm (nm) pulsed dye laser (PDL) has the capability of destroying NMSC through nonspecific thermal necrosis. The purpose of this study was to understand recurrence of NMSC on dorsal hands of older patients after one or two treatments using 595 nm PDL.

METHODS:

A retrospective chart review identified 147 cases of NMSC located on the dorsal hands treated with 595 nm PDL. Cases of basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) were included. All patients received one to two treatments with PDL. The primary outcome was the recurrence of carcinoma.

RESULTS:

Among NMSC cases treated with PDL, recurrence occurred in 12 patients (8.2%). No cases of BCC recurred during the study period. Recurrence of SCC was 4.7% for SCC in situ and 10.4% recurrence for invasive SCC (p = 0.34). Among 71 patients treated once, recurrence occurred in 10 patients (14.1%), and among 76 cases treated twice, recurrence occurred in 2 patients (2.6%, p = 0.01).

CONCLUSION:

Two treatments of PDL for NMSC on the dorsal hands of older patients was well tolerated, had low recurrence, and seemed more effective than one treatment.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Carcinoma Basocelular / Lasers de Corante Limite: Humans Idioma: En Revista: Lasers Med Sci Assunto da revista: BIOTECNOLOGIA / RADIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Carcinoma Basocelular / Lasers de Corante Limite: Humans Idioma: En Revista: Lasers Med Sci Assunto da revista: BIOTECNOLOGIA / RADIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos