Platelet FcγRIIA: An emerging regulator and biomarker in cardiovascular disease and cancer.
Thromb Res
; 238: 19-26, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38643522
ABSTRACT
Platelets, anucleate blood cells derive from megakaryocytes, are involved in cardiovascular diseases and tumors. FcγRIIA, the only FcγR expressed on human platelets, is known for its role in immune-related diseases. A growing body of evidence reveals that platelet FcγRIIA is a potential target for the prevention and control of cardiovascular disease and cancer, and is an advantageous biomarker. In this review, we describe the structure and physiological function of platelet FcγRIIA, its regulatory role in cardiovascular disease and cancer, and its potential clinical application.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plaquetas
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Doenças Cardiovasculares
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Receptores de IgG
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Neoplasias
Limite:
Animals
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Humans
Idioma:
En
Revista:
Thromb Res
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China