Natural products with potential hypoglycemic activity in T2DM: 2019-2023.
Phytochemistry
; 223: 114130, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38714289
ABSTRACT
As currently the most common metabolic disease, type 2 diabetes mellitus (T2DM) has shown a continuous increase in the number of patients in recent decades. Most anti-T2DM drugs tend to cause some side effects. Given the pathogenesis of T2DM, natural products have emerged as an important source of anti-T2DM drugs. This article reviews natural products with potential hypoglycemic activity from 2019 to 2023. A total of 200 previously natural products were discovered on SciFinder, PubMed and Web of Science. These products were categorized based on their structural frameworks and their biological activities were summarized. Although the mechanisms of action of most compounds are unclear, these compounds could still serve as candidates for the development of lead compounds. Therefore, further structure and activity research of natural products will significantly contribute to the development of potential anti-T2DM drugs.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Produtos Biológicos
/
Diabetes Mellitus Tipo 2
/
Hipoglicemiantes
Limite:
Humans
Idioma:
En
Revista:
Phytochemistry
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China